Article Details : |
| | Article Name : | | Frequency and association of microalbuminuria
with target organ damage in hypertensive patients
| Author Name : | | Md. MAHFUZER RAHMAN, RATINDRA NATH MONDAL1, AKTER BANU, MONI RANI, AZMERI ALAM, AKM SHAHEDUZZAMAN, MD. SHAFIUL ALAM, MD. ZAKIR HOSSAIN, MD TAYEF ANJUM | Publisher : | | Bridge Center | Article URL : | | | Abstract : | | Background: Hypertension has become as an important cause
of premature mortality and morbidity due to its major etiologic role in
the development of coronary artery disease, stroke and renal failure.
Majority of the patients died due to any of the hypertension related
complications.
Subjects and Methods: This was a descriptive cross sectional
study, carried out in Hypertension & Research Centre, Rangpur.
Assuming 5% prevalence of microalbuminuria in hypertensive patients a sample size of 73 was calculated. In this study we have taken 75
patients.
Results: During the study period, we have studied over 75
patients of both sexes. Mean age of the victims were 52.98 ±12.2 years.
Males were more common than female (62.7% vs 37.3%. Among the
study patients MA was present in 11(14.7%). MA was more in stage 2
hypertensive patient than stage 1 hypertensive patients ( vs 9.43%) (p
=0.047). Among the study population 7 (9.33%) were obese. MA was
more in obese patients than overweight and normal body weight
patients (p=0.404). In the study among the target organ lesion
retinopathy was 34.7%, IHD 30.7%, LVH 28% and least common was
stroke 17.3%. A statistically significant association was found between
LVH and microalbuminuria (p=0.009) (OR=6.25), between IHD and
microalbuminuria (p=0.003) (OR=8.71) and between
microalbuminuria and retinopathy (p = 0.035) (OR=4.14).
Conclusion: In our study frequency of MA was 14.7% and a
significant association was found between microalbuminuria and
target organ damage of hypertension (LVH, IHD, and retinopathy). | Keywords : | | Microalbuminuria, target organ, retinopathy |
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