European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
Fecal Microbiota Transplantation for Clostridium Difficile Infection
Author Name :
DOSIEAH POOJA DOOKHUN MUHAMMAD NABEEL LIN HUI-HUA ZHANG ZHEN-YU
Publisher :
Bridge Center
Article URL :
Abstract :
The increased prevalence of Clostridium difficile infection (CDI) has cause significant clinical and economic burden. There has been a major challenge for recurrent CDI due to poor response to standard therapeutic approach. Following antibiotic treatment, the intestinal flora is disturbed and this constitutes a major risk of CDI. The emergence of fecal microbiota transplantation (FMT) has brought an efficient treatment concept towards CDI. FMT involves the reconstitution of the normal intestinal microbial homeostasis. The use of FMT has become an acceptable and successful treatment for recurrent CDI where conventional therapy has failed. CDI is the main cause of pseudomembranous colitis and is associated with high mortality and morbidity. Risk of CDI is highly due to the use of broadspectrum antibiotic, increasing age and hospitalization. Ensuring a normal colonization of healthy intestinal microbiota can alleviate the symptoms of recurrent CDI and this can be done by FMT techniques. Recently, FMT has become an interesting therapeutic technique clinically for a variety of diseases.
Keywords :
Clostridium difficile infection (CDI), fecal microbiota transplantation (FMT), treatment CDI.
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