European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
Effect of Hypothyroidism on renal function tests in Indian patients in 2012
Author Name :
WALED MOHAMED ALSALMI LAILA HAMED FARAJ SHAGLOUF ABDU ALHAMEED .A. ALI AZZWALI SAPNA SMITH LAL
Publisher :
Bridge Center
Article URL :
Abstract :
Background: Thyroid dysfunction causes significant changes in kidney function, both hypothyroidism and hyperthyroidism affect renal blood flow, GFR, tubular function, electrolytes homeostasis, electrolyte pump functions, and kidney structure Objective: The aim of this study was to investigate the effect of thyroid dysfunction (hypothyroidism) on biochemical markers of kidney in hypothyroid patients. TSH was used as a marker of the thyroid status. Methods: Thyroid function tests (T3, T4 and TSH levels) were assayed in 70 subjects. Based on TSH levels, subjects were classified as euthyroid (n=47), hypothyroidism (n=23). BUN, serum CTN, UA, serum Na, serum K and serum Cl were studied in patients with hypothyroidism and euthyroid subjects. Results: BUN, serum CTN, UA and K levels were significantly increased in hypothyroid patients as compared to euthyroid subjects, whereas serum Na and Cl levels were significantly decreased in hypothyroid patients as compared to controls. Conclusion: This study demonstrated a significant effect of thyroid dysfunction (hypothyroidism) on biochemical markers of kidney.
Keywords :
hypothyroidism, renal function tests, Indian patients

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