Article Details : |
| | Article Name : | | Effect of Hypothyroidism on renal function tests in
Indian patients in 2012 | Author Name : | | WALED MOHAMED ALSALMI
LAILA HAMED FARAJ SHAGLOUF
ABDU ALHAMEED .A. ALI AZZWALI
SAPNA SMITH LAL | Publisher : | | Bridge Center | Article URL : | | | Abstract : | | Background: Thyroid dysfunction causes significant changes
in kidney function, both hypothyroidism and hyperthyroidism affect
renal blood flow, GFR, tubular function, electrolytes homeostasis,
electrolyte pump functions, and kidney structure
Objective: The aim of this study was to investigate the effect of
thyroid dysfunction (hypothyroidism) on biochemical markers of
kidney in hypothyroid patients. TSH was used as a marker of the
thyroid status.
Methods: Thyroid function tests (T3, T4 and TSH levels) were
assayed in 70 subjects. Based on TSH levels, subjects were classified as
euthyroid (n=47), hypothyroidism (n=23). BUN, serum CTN, UA,
serum Na, serum K and serum Cl were studied in patients with
hypothyroidism and euthyroid subjects.
Results: BUN, serum CTN, UA and K levels were significantly
increased in hypothyroid patients as compared to euthyroid subjects,
whereas serum Na and Cl levels were significantly decreased in
hypothyroid patients as compared to controls.
Conclusion: This study demonstrated a significant effect of
thyroid dysfunction (hypothyroidism) on biochemical markers of
kidney.
| Keywords : | | hypothyroidism, renal function tests, Indian patients |
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