Article Details : |
| | Article Name : | | Molecular detection of Adenovirus type 2 among
conjunctivitis patients in Khartoum state- Sudan | Author Name : | | ASMAA YOUSUF SHAMBAL
NASRALDEEN M. A. BUSH
SALWA HASSAN MOHAMED BASHEER, MUSA ABDALLA ALI, MARWA M.A MOHAMMED | Publisher : | | Bridge Center | Article URL : | | | Abstract : | | Background: Adenoviruses are a group of viruses that can
infect the membranes (tissue linings) of the respiratory tract, eyes,
intestines, and urinary tract. Diagnosis of conjunctivitis and
differentiation between bacterial, viral, and noninfectious
conjunctivitis are usually clinical. PCR and other rapid, office-based
immunodiagnostic tests can be useful especially when the
inflammation is severer.
Objective: This study aimed to detect adenovirus among
conjunctivitis infected patients to figure out the possibility of using
PCR technique to achieve that goal.
Methods: By using PCR for DNA products of 45 conjunctivitis
swabs, to detect adenovirus type 2.
The Results: Only one sample gave a positive result out of 45
samples detected (2.2%)
Conclusion: It seems to be no adenovirus spreading enough
among patients causing their eye illness, therefore other causative agents for conjunctivitis may be existence, as in Sudan most of the
year the climate not suitable for adenovirus survival as it lives in cold
and wet environments unlike what above local one. However, if any
signs suggest bacterial conjunctivitis (eg, purulent discharge), cultures
or other studies may be useful. The prevalence of adenoviral
conjunctivitis in the study population was lower than the prevalence in
other regions of the world. | Keywords : | | Conjunctivitis, Human adenoviruses (HAdVs),
polymerase chain reaction (PCR). |
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