Article Details : |
| | Article Name : | | Characterization of Renal Function and
Morphology in Hypertensive Patients Using Renal
scintigraphy | Author Name : | | HOSSAM GASMALSEED, MOHAMED E. M. GARALNABI, OTHILA ABDALAZIZ, ADIL A. MANSOUR, MOHAMED HASANEEN | Publisher : | | Bridge Center | Article URL : | | | Abstract : | | Aim: The aim of study to evaluate renal function in
hypertension patients using renogram and correlate it with age,
gender, GFR, and duration of disease.
Methods: We studied 100 hypertension patients (42Males,58
Females) mean age 60.6 years, Renal scintigraphy was done to all with
99mTc-MAG3, Renal scintigraphy (anterior and posterior images) was
obtained within 20 seconds after administration of 185-370MBq (5-
10mCi depended patient weight) of 99mTc-MAG3 and results were
evaluated quantitatively and qualitatively calculating both kidneys
function.
Results: In case of radionuclide renography, total glomerular
filtration rate (GFR) ranged from 130-40 (mean ± SD) 87. 9±17.3(male 86.8±16.3 female 88.8±18.1), correlated GFR with age decline rate was
0.82 (1.2 ml/min/years) Renal Scintigraphy demonstrated 84% Has
normal renal function with mild (AORTA- RENAL DELAY), normal
cortical and clearance phase 16% had abnormal function (unilateral
93% and bilateral 7% more affected RT kidney than left). both kidneys
show decrease renal function with age and duration of disease. The
association was stronger in person had uncontrollable and long
standing hypertensive disease. Also noted the average peak activity
decrease when the duration of disease increase.
Conclusions: Studies with 99mTc-MAG3 present high
specificity and are useful in patients with high probability for
renovascular hypertension, identifying high number of patients with
significant renal artery stenosis.
| Keywords : | | Renal Function, Hypertensive Patients
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