European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
Characterization of Renal Function and Morphology in Hypertensive Patients Using Renal scintigraphy
Author Name :
HOSSAM GASMALSEED, MOHAMED E. M. GARALNABI, OTHILA ABDALAZIZ, ADIL A. MANSOUR, MOHAMED HASANEEN
Publisher :
Bridge Center
Article URL :
Abstract :
Aim: The aim of study to evaluate renal function in hypertension patients using renogram and correlate it with age, gender, GFR, and duration of disease. Methods: We studied 100 hypertension patients (42Males,58 Females) mean age 60.6 years, Renal scintigraphy was done to all with 99mTc-MAG3, Renal scintigraphy (anterior and posterior images) was obtained within 20 seconds after administration of 185-370MBq (5- 10mCi depended patient weight) of 99mTc-MAG3 and results were evaluated quantitatively and qualitatively calculating both kidneys function. Results: In case of radionuclide renography, total glomerular filtration rate (GFR) ranged from 130-40 (mean ± SD) 87. 9±17.3(male 86.8±16.3 female 88.8±18.1), correlated GFR with age decline rate was 0.82 (1.2 ml/min/years) Renal Scintigraphy demonstrated 84% Has normal renal function with mild (AORTA- RENAL DELAY), normal cortical and clearance phase 16% had abnormal function (unilateral 93% and bilateral 7% more affected RT kidney than left). both kidneys show decrease renal function with age and duration of disease. The association was stronger in person had uncontrollable and long standing hypertensive disease. Also noted the average peak activity decrease when the duration of disease increase. Conclusions: Studies with 99mTc-MAG3 present high specificity and are useful in patients with high probability for renovascular hypertension, identifying high number of patients with significant renal artery stenosis.
Keywords :
Renal Function, Hypertensive Patients

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