European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
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Article Details :
Article Name :
Evaluation of Plasma Electrolytes (Sodium and Potassium Levels) among Sickle Cell Anemia Patients Attended to Kosti and Rabak Teaching Hospitals, Sudan
Author Name :
MOHAMMED FOUAD MOHAMMED ABBAS, ABAZAR MAHMOUD ISMAIL SIDDIG, MOHAMED OSMAN ALI, ABUBAKER KHALID ALSIDDIG, MOHAMED ELAMIN ELSAFI AJBAN
Publisher :
Bridge Center
Article URL :
Abstract :
Sickle cell anemia is a type of Hemoglobin disorder associated with biochemical abnormalities such as imbalance of electrolytes. This study was aimed to evaluate plasma sodium and potassium levels among sickle cell anemia patients attended to Kosti and Rabak teaching hospitals in Sudan during the period from August to October 2017. This is a case control study was done in seventy five sickle cell anemia patients and fifty healthy controls. About 3ml of venous blood were collected using sterile syringes and poured into lithium heparin containers then centrifuged to obtained plasma which use to measure sodium and potassium levels using Ion selective electrode. This study showed that the levels of sodium and potassium were significantly less in case group (adult and children) when compared with healthy controls group (134 ± 7mmol/L, 140±3mmol/L for sodium in case and control group respectively . while 3.7±0.6 mmol/l, 4.3±0.57 mmol/l for potassium in case and control group respectively). This study has explained that sodium and potassium levels have a role in sickle cell anemia which could be used in designing of the better management of sickle cell anemia patients.
Keywords :
Haemoglobinopathy, Sickle cell anemia, Electrolytes, polymerization, hemoglobin S.
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