European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
Effect of Tenofovir, an antiretroviral Drug in Renal Functional among Patients with Human Immunodeficiency Virus
Author Name :
Ehab Abdelmoneim, Yassir B. F. Basher, Mohamed A. M. Salih
Publisher :
Bridge Center
Article URL :
Abstract :
This study was conducted during the period from April 2015 to July 2015 to assess the Effect of Tenofovir, an antiretroviral drug in renal functional among Patients with human immunodeficiency virus. Fifty patients with HIV were selected as a test group from the Voluntary Counseling and Testing Center, Blue Nile state, Sudan. The test group was compared with a control group which included 50 healthy volunteers. Blood specimens were collected from both groups and urea and creatinine were estimated. Age and gender of the test group were matched with the control group. Spectrophotometeric methods were used for measurement of urea and creatinine. Statistical package for social science (SPSS version 16) computer software was used for data analysis. The results indicated a significant increase in the mean of the plasma levels of urea of the test group when compared with the control group (38 ± 6 mg/dL) versus (25± 7 mg/dL) (p=0.000), and a significant elevation in the mean of plasma levels creatinine in HIV patients with Tenofovir, an antiretroviral drug when compared with healthy volunteers (2.2± 0.5 mg/dL) versus (0.7± 0.1 mg/dL) (p=0.000). In conclusion the urea and creatinine levels was invariably higher in HIV patients with Tenofovir, an antiretroviral drug than in those Health volunteers.
Keywords :
Tenofovir, an antiretroviral drug, urea, creatinine

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