Article Details : |
| | Article Name : | | Effect of Tenofovir, an antiretroviral Drug in Renal
Functional among Patients with Human
Immunodeficiency Virus | Author Name : | | EHAB ABDELMONEIM, YASSIR B. F. BASHER, MOHAMED A. M. SALIH1 | Publisher : | | Bridge Center | Article URL : | | | Abstract : | | This study was conducted during the period from April 2015 to
July 2015 to assess the Effect of Tenofovir, an antiretroviral drug in
renal functional among Patients with human immunodeficiency virus.
Fifty patients with HIV were selected as a test group from the
Voluntary Counseling and Testing Center, Blue Nile state, Sudan. The
test group was compared with a control group which included 50
healthy volunteers. Blood specimens were collected from both groups
and urea and creatinine were estimated. Age and gender of the test
group were matched with the control group. Spectrophotometeric
methods were used for measurement of urea and creatinine. Statistical
package for social science (SPSS version 16) computer software was
used for data analysis. The results indicated a significant increase in
the mean of the plasma levels of urea of the test group when compared
with the control group (38 ± 6 mg/dL) versus (25± 7 mg/dL) (p=0.000), and a significant elevation in the mean of plasma levels creatinine in
HIV patients with Tenofovir, an antiretroviral drug when compared
with healthy volunteers (2.2± 0.5 mg/dL) versus (0.7± 0.1 mg/dL)
(p=0.000). In conclusion the urea and creatinine levels was invariably
higher in HIV patients with Tenofovir, an antiretroviral drug than in
those Health volunteers. | Keywords : | | Tenofovir, an antiretroviral drug, urea, creatinine. |
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