European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
Frequency of MecA, Van A and Van B Genes in Staphylococcus aureus isolates among pediatric clinical specimens in Khartoum Hospitals 2017
Author Name :
Mohammed A Neel, Mogadam Baher Eldin Mogadam, Ranya S Mohamed, Nora A Osman, Mahadi H Abdallah, Mogadam Baher Eldin Mogadam
Publisher :
Bridge Center
Article URL :
Abstract :
Methicillin resistant Staphylococcus aureus (S. aureus) (MRSA) infections strains is increases number in global health threat. Vancomycin is one of the very limited options in treating such infections. The emergence of vancomycin-resistant S. aureus (VRSA) is therefore a great concern in clinical settings. During recent years, the incidence of vancomycin-intermediate S. aureus (VISA) and vancomycin resistant S. aureus has increased in the world. This study was conducted to estimate the frequency of MecA and van A, B genes in Staphylococcus aureus among children. Different clinical samples were collected from 81 children with an age range from (1-15) years old that was diagnosed as Staphylococcus aureus infections in Khartoum hospitals during period from October 2017 to December 2017. Out of 81 Staphylococcus aureus isolated which had been confirmed phenotypically by Biochemical method from different children clinical samples and genotypiclly by 16s gene and detect of MecA and van A and B after doing antibiotic susceptibility of Methicillin and Vancomycin resistant. Among Staphylococcus aureus identified, the antibiotic susceptibility result is 94% Methicillin resistant and 44% Vancomycin resistant .The (PCR) result is 28/50 revealed that 56% were positive for Mec A and none for van A and B. The high frequency of circulating MecA gene highlights and none of Van A, B.
Keywords :
MRSA VRSA, MecA and Van A, B.

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