| Article Details : |
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| | | Article Name : | | | Frequency of MecA, Van A and Van B Genes in
Staphylococcus aureus isolates among pediatric
clinical specimens in Khartoum Hospitals 2017 | | Author Name : | | | MOHAMMED A NEEL, MOGADAM BAHER ELDIN MOGADAM
RANYA S MOHAMED, NORA A OSMAN
MAHADI H ABDALLAH, MOGADAM BAHER ELDIN MOGADAM1 | | Publisher : | | | Bridge Center | | Article URL : |  | | | Abstract : | | | Methicillin resistant Staphylococcus aureus (S. aureus)
(MRSA) infections strains is increases number in global health threat.
Vancomycin is one of the very limited options in treating such
infections. The emergence of vancomycin-resistant S. aureus (VRSA) is
therefore a great concern in clinical settings. During recent years, the
incidence of vancomycin-intermediate S. aureus (VISA) and
vancomycin resistant S. aureus has increased in the world. This study
was conducted to estimate the frequency of MecA and van A, B genes in
Staphylococcus aureus among children. Different clinical samples
were collected from 81 children with an age range from (1-15) years old that was diagnosed as Staphylococcus aureus infections in Khartoum
hospitals during period from October 2017 to December 2017. Out of
81 Staphylococcus aureus isolated which had been confirmed
phenotypically by Biochemical method from different children clinical
samples and genotypiclly by 16s gene and detect of MecA and van A
and B after doing antibiotic susceptibility of Methicillin and
Vancomycin resistant. Among Staphylococcus aureus identified, the
antibiotic susceptibility result is 94% Methicillin resistant and 44%
Vancomycin resistant .The (PCR) result is 28/50 revealed that 56%
were positive for Mec A and none for van A and B. The high frequency
of circulating MecA gene highlights and none of Van A, B. | | Keywords : | | | MRSA VRSA, MecA and Van A, B.
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