| Article Details : |
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| | | Article Name : | | | Lipid Profile and Other Risk Factors in Prevalence
of Cholelithiasis: A Review | | Author Name : | | | NIDA NAZAR1, SHAHIDA KAREEM
NAHEEDA JALAL
MARYUM DAWOOD, SYED MUHAMMED ISHAQUE, KHALID MEHMOOD | | Publisher : | | | Bridge Center | | Article URL : |  | | | Abstract : | | | The objective of this review is to high light the risk factors of
gall bladder stone formation. As it is a general gastrointestinal disease
in developed as well as in developing countries approximately ten to
fifteen percent of adult population suffering from this aliment.
Majority of patient’s showed severe abdominal pain, which leads to
surgical interventions. Numerous other factors including certain
diseases may play a key role in formation of stones. The major cause is
reduced metabolism of bile acids, cholesterol and bilirubin. In the case
of cholelithiasis, the serum lipid profile plays a significant role
especially in formation of cholesterol gallstones. The studies of 30 years
indicated that the lipid disturbance noticed in half of the patients of cholelithiasis. This condition could increase the chance of stroke and
coronary heart disorders. Evidences from previous studies suggest that
cholelithiasis is more common in females than male. In several studies,
eighty percent of females are effected with gall bladder stone disease.
The synthesis of the bile acid decreases with the elderly age. However
the findings of this study is to avoid fat rich food, regulate
dyslipidemia, less use of saturated fatty acids, control of weight gain
and assessment of lipid profile on shortly intervals and may be use of
anti-hyperlipidemia drugs. Thus, these precautionary measures as well
as medication may help in decreasing the formation of gall stone
disease risk. Therefor the pharmaceutical companies must high light
the importance of anti-lipedema drugs for treatment and prevention of
cholelithiasis. | | Keywords : | | | Gallstones; Risk factors; Serum lipid profile; Gender;
Prevention.
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