| Article Details : |
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| | | Article Name : | | | PLLA Synthesis and Membrane Production through
Rotary Jet Spinning Process
Poly (L-lactic acid) Synthesis and Physico-chemical
Analysis | | Author Name : | | | BÁRBARA ETRURI CIOCCA1, NAHIEH TOSCANO MIRANDA, GUINEA BRASIL CAMARGO CARDOSO
ANA AMÉLIA RODRIGUES
ANA FLÁVIA PATTARO, ANDRÉ LUIZ JARDINI MUNHOZ
RUBENS MACIEL FILHO | | Publisher : | | | Bridge Center | | Article URL : |  | | | Abstract : | | | Poly (L-lactic acid) (PLLA) is a well-established polymer,
which is widely used in a wide range of fields; however, it is a high
cost material, presenting great difficulties for its purchase. Therefore,
the present work proposes PLLA synthesis in the laboratory, as an
alternative to turn this more feasible; its processing through rotary jet
spinning to obtain fibrous membranes; its physico-chemical analyses
for material characterization; and, in vitro cell viability analyses with
osteoblasts and fibroblasts. Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Energy Dispersive Spectroscopy
(EDS), and Live/Dead® assays were the characterization analyzes of
the obtained membrane. PLLA membranes had initial degradation at
200 °C, and none harmful chemical elements were present. In vitro test
verified the compatibility of the membranes with two cell lines,
indicating a possible and potential application of these membranes in
the medical field. | | Keywords : | | | Physico-chemical analysis, PLLA, Poly (L-lactic acid),
rotary jet spinning. |
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