European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
PLLA Synthesis and Membrane Production through Rotary Jet Spinning Process Poly (L-lactic acid) Synthesis and Physico-chemical Analysis
Author Name :
Bárbara Etruri Ciocca, Nahieh Toscano Miranda, Guinea Brasil Camargo Cardoso, Ana Amélia Rodrigues, Ana Flávia Pattaro, André Luiz Jardini Munhoz, Rubens Maciel Filho
Publisher :
Bridge Center
Article URL :
Abstract :
Poly (L-lactic acid) (PLLA) is a well-established polymer, which is widely used in a wide range of fields; however, it is a high cost material, presenting great difficulties for its purchase. Therefore, the present work proposes PLLA synthesis in the laboratory, as an alternative to turn this more feasible; its processing through rotary jet spinning to obtain fibrous membranes; its physico-chemical analyses for material characterization; and, in vitro cell viability analyses with osteoblasts and fibroblasts. Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Energy Dispersive Spectroscopy (EDS), and Live/Dead® assays were the characterization analyzes of the obtained membrane. PLLA membranes had initial degradation at 200 °C, and none harmful chemical elements were present. In vitro test verified the compatibility of the membranes with two cell lines, indicating a possible and potential application of these membranes in the medical field.
Keywords :
Physico-chemical analysis, PLLA, Poly (L-lactic acid), rotary jet spinning.

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