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| | | Article Name : | | | Determination of Phytochemical Components and the Antimicrobial Potency of Bryophyllum pinnatum Leaf Extracts against Some Clinical Bacteria and Fungi Isolates | | Author Name : | | | Kabiru Haruna Ibrahim, Lawan Sani Ahmad, Muhammad Sulaiman, Manniru Ali Abullahi | | Publisher : | | | Bridge Center | | Article URL : |  | | | Abstract : | | | The Bryophyllum pinnatum plant is one of the many medicinal plants that traditional healers use to treat a variety of illness. This study was aimed to identify the ideal phytochemical components and antimicrobial potency of B. pinnatum plant leaf extracts. Seven different extraction solvents of increasing polarity were used to assess the phytochemical properties and biotherapeutic potential of the plant. The fresh leaves were collected from the Garden of Plant Biology Department of Bayero University, Kano. Following the normal and standard procedure, the leaves were air dried and ground into powder and used for extraction, to determine the presence of secondary metabolites. Then follows by antimicrobial efficacy with different concentrations (25, 50, 75 and 100 mg/ml) of the extracts. The microbial strains were collected from Murtala Muhammad General Hospital, Kano. Nine microbes were tested using agar disc diffusion method and commercially prepared antibiotics were used as positive control. The antimicrobial potency of each extract concentration was assessed by measuring the zone of inhibitions against the test organisms. Various phytochemicals were presents, according to the data, the highest quantities of alkaloids, flavonoids, saponins, tannins and terpenoids as well as moderate concentration of phenolic were found in the methanol extract. When employing petroleum ether, resins were discovered in excess quantity. The outcomes also revealed the average zone of inhibitions for different plant extract at various doses. The findings showed that, when compared to other extracts, the ethyl acetate and methanol plant extract of B. pinnatum have higher antimicrobial potency, with methanol having the strongest antimicrobial effect (21.4±0.2 and 24.4±0.2) against E. coli isolate at 75 and 100 mg/ml respectively. The antimicrobial potency of other extracts was moderate to weak. The test organism | | Keywords : | | | Bryophyllum pinnatum leaves, phytochemicals and antimicrobial potency |
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