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| | | Article Name : | | | A Review of the Mechanics, Prevalence, Affecting Variables, and Different Strategies for Antibiotic Resistance | | Author Name : | | | Haider Qassim Raheem | | Publisher : | | | Bridge Center | | Article URL : |  | | | Abstract : | | | Since their discovery in the early 1900s, antibiotics have transformed medicine and saved countless lives. However, the worrying increase in antibiotic resistance has eclipsed the history of antibiotics. The unrelenting adaptability of microbes is the cause of this global disaster caused by the overuse and abuse of antibiotics. The history of antibiotics and the subsequent development of antibiotic resistance are examined in this article. It explores the methods bacteria use to become resistant, emphasizing the grave repercussions of medication resistance, such as worse patient care, higher death rates, and rising medical expenses. The article describes the most recent tactics for combating drug-resistant microbes, including cutting-edge methods like phage treatment,CRISPR-Cas9 technology,and the investigation of natural chemicals.Additionally, it looks at how antibiotic resistance significantly affects medication development,making the search for new antibiotics financially difficult.The constraints and difficulties in creating innovative Antibiotics and regulatory roadblocks that impede advancement in this crucial area are covered. There are suggestions made for altering the regulatory procedure to speed up the creation of antibiotics. Major pharmaceutical companies departure from antibiotic research is discussed, along with possible ways to pique their interest again. The article highlights global alliances and collaborations while outlining efforts to overcome financial obstacles and encourage the development of antibiotics | | Keywords : | | | antibiotic resistance; drug designing; horizontalgene transfer; public and agricultural health. |
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